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Green chemistry approach to the synthesis of 2-aryl-4-ferrocenyl-quinoline derivatives under microwave irradiation

✍ Scribed by Ning Ma; Han Lu; Feiyue Wu; Ge Zhang; Bo Jiang; Feng Shi; Yuan Gao; Shujiang Tu

Publisher
Journal of Heterocyclic Chemistry
Year
2011
Tongue
English
Weight
83 KB
Volume
48
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

A clean and expeditious route for the synthesis of 2‐aryl‐4‐ferrocenyl‐quinoline derivatives through microwave‐assisted multicomponent reaction of ferrocenecarboxaldehyde with ketone and dimedone in the presence of ammonium acetate using water as reaction media at 100^°^C is described. This procedure lends itself well to combinatorial methods, providing the target heteropolymetallic compounds in excellent yield. J. Heterocyclic Chem., (2011).

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