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Green chemistry approach to the synthesis of 2-amino-4-aryl-6-ferrocenyl-pyridine derivatives by a one-pot reaction in aqueous medium

✍ Scribed by Qiya Zhuang; Runhong Jia; Shujiang Tu; Junyong Zhang; Bo Jiang; Yan Zhang; Changsheng Yao


Publisher
Journal of Heterocyclic Chemistry
Year
2007
Tongue
English
Weight
410 KB
Volume
44
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

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A clean and facile green chemistry method for the synthesis of a series of 2‐amino‐4‐aryl‐6‐ferrocenylpyridine derivatives was afforded. The products were synthesized via the one‐pot reaction of aromatic aldehyde, malononitrile or ethyl cyanoacetate, acetylferrocene and ammonium acetate in aqueous medium under microwave irradiation and conventional heating conditions without catalyst. This method had several advantages such as higher yield, lower cost, reduced environmental impact, and convenient procedure.


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Green Chemistry Approach to the Synthesi
✍ Qiya Zhuang; Runhong Jia; Shujiang Tu; Junyong Zhang; Bo Jiang; Yan Zhang; Chang πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons βš– 22 KB πŸ‘ 2 views

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