✦ LIBER ✦

An efficient and greener approach to the synthesis of 3,5-dicyanopyridin-2(1H)-one derivatives in aqueous media under microwave irradiation conditions

✍ Scribed by Runhong Jia; Shujiang Tu; Yan Zhang; Bo Jiang; Junyong Zhang; Changsheng Yao; Feng Shi

Publisher: Journal of Heterocyclic Chemistry
Year: 2007
Tongue: English
Weight: 278 KB
Volume: 44
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570440533

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✦ Synopsis

Abstract

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A facile and greener synthesis of a series of 3,5‐dicyanopyridin‐2(1__H__)‐one derivatives was accomplished via the one‐pot reaction of aldehyde, malononitrile and sodium hydroxide in aqueous media under microwave irradiation. This method had several advantages such as shorter route and time, lower cost, reduced environmental impact.

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