Greatly enhanced bioavailability of theophylline on postprandial administration of a sustained release tablet
β Scribed by M. Lagas; J. H. G. Jonkman
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 651 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0031-6970
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Quinidine gluconate 324 mg sustained release tablets (Quinaglute) was administered as a single dose to 15 healthy male subjects following an overnight fast, immediately following a high fat (HF) breakfast or immediately following a low fat (LF) breakfast. Serum samples were obtained over a 48 h peri
## Abstract The bioavailability of quinidine sulfate after oral administration of a commercial sustainedβrelease quinidine tablet was compared with that of oral quinidine sulfate solution in 18 normal subjects. Three hundred milligrammes of each product was administered to each subject in standard