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Disposition and clinical pharmacokinetics of theophylline after administration of a new sustained release tablet

✍ Scribed by J. H. G. Jonkman; W.Chr Berg; K. Vries; R. A. Zeeuw; R. Schoenmaker; N. Grimberg


Publisher
Springer
Year
1981
Tongue
English
Weight
652 KB
Volume
21
Category
Article
ISSN
0031-6970

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Nitroglycerin was administered to eight healthy volunteers in the form of sublingual tablets, oral sustained-release tablets, and an oral solution. Blood samples were collected for measurement of nitroglycerin and its two isomeric glyceryl dinitrate metabolites. Blood pressure and pulse rate were mo