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GRB10 binds to LRP6, the Wnt co-receptor and inhibits canonical Wnt signaling pathway

✍ Scribed by Norio Tezuka; Anthony M.C. Brown; Shin-ichi Yanagawa

Book ID
116294622
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
710 KB
Volume
356
Category
Article
ISSN
0006-291X

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## Abstract It is unclear whether the mutation spectra in WNT genes vary among distinct types of colorectal tumors. We have analyzed mutations in specific WNT genes in a cohort of 52 colorectal tumors and performed a meta‐analysis of previous studies. Notably, significant differences were found amo