Silibinin inhibits Wnt/β-catenin signaling by suppressing Wnt co-receptor LRP6 expression in human prostate and breast cancer cells

Inhibition of Wnt signaling by cucurbita

Inhibition of Wnt signaling by cucurbitacin B in breast cancer cells: Reduction of Wnt-associated proteins and reduced translocation of galectin-3-mediated β-catenin to the nucleus

✍ Sumana Dakeng; Suwit Duangmano; Weena Jiratchariyakul; Yaowalak U-Pratya; Oliver 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 736 KB

## Abstract The cucurbitacins are tetracyclic triterpenes found in plants of the family Cucurbitaceae. Cucurbitacins have been shown to have anti‐cancer and anti‐inflamatory activities. We investigated the anti‐cancer activity of cucurbitacin B extracted from Thai medicinal plant __Trichosanthes cu