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Graphene Field-Effect Transistor Biosensors

✍ Scribed by Shiyu Wang, Zakir Hossain, Yan Zhao, Tao Han

Publisher
Springer
Year
2021
Tongue
English
Leaves
123
Category
Library
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✦ Synopsis

In this monograph, the graphene-based field-effect transistor (FET) biosensors are shown to be an emerging sensing platform. Divided into two parts the first set of chapters are devoted to basic knowledge of graphene, graphene FET and its biosensing. In the second part of this book the applications of graphene FET biosensors combined with various biotechnologies are presented. As well as discussing the existing technologies the authors also introduce their own ideas and concepts. Finally the remaining problems in graphene FET biosensors are discussed, along with proposed solutions and prospects for future applications. This monograph allows readers to grasp the basic knowledge and future direction of graphene-based FET biosensors.



✦ Table of Contents

Preface
Acknowledgments
Contents
1 Fundamental of Graphene
1.1 Graphene Conductive Ink
1.2 Graphene Supercapacitor
1.3 Microbial Fuel Cells
1.4 Graphene Flexible Sensing
1.5 Graphene Nanogenerator
1.6 Thermal Applications
1.7 Biomedical Applications
1.7.1 Drug Delivery
1.7.2 Cell Imaging
1.7.3 DNA Sequencing
1.7.4 Tumor Therapy
1.7.5 Biological Detection
1.7.6 Graphene Biosafety Research
References
2 Graphene Electrical Characteristics
2.1 Room Temperature Electrical Characteristics
2.2 Low-Temperature Electrical Characteristics
2.2.1 Magic Angle Graphene
2.2.2 Moiré Pattern
References
3 Graphene Manufacture
3.1 Mechanical Exfoliation Method
3.2 Chemical Vapor Deposition
3.2.1 Pretreatment
3.2.2 CVD Graphene
3.2.3 Transferring
3.3 Epitaxial Growth
3.3.1 Epitaxial Graphene Preparation
3.3.2 Graphene Characterization
3.4 Other Methods
3.4.1 Directly Synthesis on SiO2
3.4.2 Reduced Graphene Oxide (R-GO)
References
4 Graphene Field-Effect Transistor Biosensor
4.1 Electrical Double Layer
4.1.1 Stern Model (1924)
4.1.2 BDM Model (1963)
4.2 Debye Length
4.3 Graphene Field-Effect Transistor
4.4 Graphene Field-Effect Transistor Biosensors
4.5 Mechanism of the Graphene Field-Effect Transistor Biosensors
4.6 Biological Applications
References
5 Graphene FET Biosensor Based on the Avidin–Biotin Technology
5.1 Background
5.2 Biotinylated Biomolecules Detection
5.2.1 Device Fabrication
5.2.2 Graphene Modification
5.2.3 Quantitative Detection
5.2.4 Specificity of the Sensor
5.2.5 Exogenous Biotin Interferences
5.2.6 Comparative Sensitivity and Practical Applicability
References
6 Graphene FET Biosensor Based on the Antigen–Antibody Interaction
6.1 Tumor Marker
6.2 Other Biomarkers
References
7 Graphene FET Biosensor Based on the Base Pair
7.1 COVID-19 Detection
References
8 Graphene FET Biosensor Based on the Aptamer Technology
References
9 Graphene FET Biosensor Based on the Concanavalin A
9.1 Adsorption
9.2 Dissociation
References
10 Challenges and Outlook
10.1 Standardization of Transfer and Modification
10.2 Signal Interference
10.3 Outlook
References
11 Conclusions and Future Works
11.1 Conclusions
11.2 Future Works
Index

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