The "aside method" has been applied to the preparation of a 2amino-2-deoxy-a-Q-galactosyl-Q-m-inositol disaccharide, using silver perchlorate and silver carbonate as the coupling reaction catalysts. A family of glycosyl phosphatidyl inositols (GPI) has been recognized recently as versatile anchor sy
Glycosyl-inositol derivatives I. Synthesis of 1-substituted chiro-inositol derivatives
β Scribed by Frank Tagliaferri; Wang Sho-Nong; William K Berlin; Robert A Outten; T.Y Shen
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 214 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0040-4039
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Optically pure 1D-chiro-inositol (DCI) has been synthesized from optically inactive myo-inositol practically in four steps. The crystalline nature of most intermediates and the utilization of inexpensive reagents facilitate the economical mass production of DCI, which is expected to be used in the f
The reduction of a-keto esters derived from (IL)-1,2;5,6-biscyclohexylidene-3-terrbutyldimethysilyl-chiro -inositol with Selectride@ proceeded with high diastereoselectivity to afford the corresponding a-hydroxy esters. Addition of l&Crown-6 led to dramatic changeover in diastereofacial selectivity.