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Glycogen Detection by in Vivo 13C NMR: A Comparison of Proton Decoupling and Polarization Transfer

✍ Scribed by M. Saner; G. Mckinnon; P. Boesiger

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
565 KB
Volume
28
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

The performance of gated proton decoupling and polarization transfer with respect to glycogen detection by ^13^C NMR was investigated. Experiments were performed on a 1.5 T whole‐body scanner using a ^13^C surface coil in combination with a proton head coil. Spectra were acquired from a glycogen phantom and from the lower leg of a healthy volunteer using proton decoupling and the polarization transfer method SINEPT. The signal strength of the C~1~ resonance of glycogen was determined and compared to a reference spectrum acquired without any form of sensitivity enhancement. In the phantom experiment both decoupling and SINEPT produced a signal gain of 3.5. Under in vivo conditions, the signal gain was approximately 2.5 for both techniques. We conclude that decoupling and polarization transfer are equivalently useful techniques for glycogen detection.© 1992 Academic Press,Inc.

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