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Glycine and D-serine decrease MK-801-induced hyperactivity in mice

✍ Scribed by M. Nilsson; A. Carlsson; M. L. Carlsson

Publisher
Springer
Year
1997
Tongue
English
Weight
863 KB
Volume
104
Category
Article
ISSN
1435-1463

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MK-801, a noncompetitive antagonist of the Nmethyl-D-aspartate (NMDA) receptor, stimulated an outbred strain of NIH Swiss mice to display discrete episodes of explosive jumping behavior, designated as "popping." The rapid onset of the MK-801-induced "popping" seems to follow the rapid distribution o