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The N-Methyl-D-aspartate (NMDA) receptor antagonist dizocilpine (MK-801) suppresses enfturane-induced opisthotonus in mice

✍ Scribed by Hisao Komatsu; Junko Nogaya; Daisuke Anabuki; Kenji Ogli


Publisher
Springer
Year
1993
Tongue
English
Weight
282 KB
Volume
7
Category
Article
ISSN
0913-8668

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N-Methyl-d-aspartate receptor antagonist
✍ Satoshi Goto; Kojiro Korematsu; Nobuhiro Inoue; Kazumichi Yamada; Taro Oyama; Sh πŸ“‚ Article πŸ“… 1993 πŸ› Springer-Verlag 🌐 English βš– 601 KB

The present study shows that systemic administration of the selective, non-competitive N-methyl-D-aspartate antagonist MK-801 [(+)-5-methyl-10,11-dihydroxy-5H-dibenzo (a,d)-cyclohepten-5,10-imine] dose-dependently induces ipsiversive rotational behavior in the rats with a unilateral striatal lesion