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Glutathione Turnover in Cultured Astrocytes: Studies with [15N]Glutamate

โœ Scribed by Marc Yudkoff; David Pleasure; Lynn Cregar; Zhi-Ping Lin; Ilana Nissim; Janet Stern; Itzhak Nissim


Book ID
111175889
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
923 KB
Volume
55
Category
Article
ISSN
0022-3042

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L-lactate inhibits L-cystine/L-glutamate
โœ Yutaka Koyama; Yuji Kimura; Hitoshi Hashimoto; Toshio Matsuda; Akemichi Baba ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 106 KB

In several brain pathologies, the level of brain L-lactate increases. The stimulation of L-lactate production is a detrimental factor in promoting neuronal cell damage and astrocytic dysfunction. Astrocytic glutathione metabolism has an important role to protect brain cells against oxidative stress.