Glutathione S-transferase genotypes as risk factors for head and neck cancer
โ Scribed by Zoltan Trizna; Gary L. Clayman; Margaret R. Spitz; Katrina L. Briggs; Helmuth Goepfert
- Book ID
- 117027507
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 345 KB
- Volume
- 170
- Category
- Article
- ISSN
- 0002-9610
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๐ SIMILAR VOLUMES
Background. We sought to evaluate the estimated risk of GSTM1 null genotype and squamous cell carcinoma of the head and neck (SCCHN). Methods. The studies done so far for GSTM1 null genotype as a risk factor associated with head and neck cancer are not conclusive and have shown conflicting results.
Background. The purpose of this study was to evaluate the prognostic ability of polymorphisms of three genes involved in the metabolism of tobacco carcinogens (GSTT1, GSTM1, GSTP1) and one polymorphism of a DNA repair gene (XRCC1) for patients diagnosed with squamous cell carcinoma (SCC). Methods.