GLUTAMATE DEHYDROGENASE ACTIVITY IN AMYOTROPHIC LATERAL SCLEROSIS
โ Scribed by Reynolds, GavinP.
- Book ID
- 123298920
- Publisher
- The Lancet
- Year
- 1988
- Tongue
- English
- Weight
- 184 KB
- Volume
- 332
- Category
- Article
- ISSN
- 0140-6736
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๐ SIMILAR VOLUMES
Glutamate levels were determined in the fasting plasma of 22 patients with early-stage primary amyotrophic lateral sclerosis (ALS) and compared to those of healthy and diseased controls. There was a significant increase (by approximately loo%, p < 0.0005) in the plasma glutamate of the ALS patients
## Glutamate transport is critical for synaptic inactivation of glutamate and prevention of excitotoxicity. The following four glutamate transporters have been identified in human brain: FL4AT1, EAAT2, EAAT3, and W T B Deficient glutamate transport has been identified in the motor cortex and the s