We investigated the effects of two anti-inflammatory cytokines, interleukin (IL)-4 and IL-10, on the production of two proinflammatory cytokines, tumor necrosis factor (TNF)-alpha and IL-6, induced by titanium-alloy (Ti6Al4V) particles. Human monocytes isolated from the peripheral blood of six healt
Glucocorticoids suppress the production of interleukin 4 by human lymphocytes
β Scribed by Chang You Wu; Christine Fargeas; Toshiharu Nakajima; Guy Delespesse
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 312 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Human interleukin 4 (IL 4) acts on various hematopoietic cell types through interaction with a specific cell surface receptor (IL 4R), whose cDNA has been cloned. We have produced a cDNA encoding a soluble form of the extracellular domain of the human IL 4R (sIL 4R) and describe here th
## Abstract These studies were designed to determine the degree of overlapping between cytolytic function and lymphokine production among peripheral blood human T lymphocytes. T8^+^ and T4^+^ cells were obtained by sorting purified T cells using the fluorescenceβactivated cell sorter (FACS) and clo
We investigated the in vitro effects of factors secreted by 3 freshly explanted human colorectal-carcinoma (CRC) cell lines on lymphocyte proliferation, IL-2-receptor expression, LAK-cell generation and cytokine secretion. We found that the supernatants of all 3 CRC cell lines inhibited T-cell proli
Background. The role of cytokines in tumor regression is now well established. The major limitation for the clinical use of cytokines is the lack of a simple and effective protocol for the local and sustained delivery of cytokines to the tumor milieu. This study reports suppression of human head and