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Glucocerebrosidase mutations are not a common risk factor for Parkinson disease in North Africa

✍ Scribed by Kenya Nishioka; Carles Vilariño-Güell; Stephanie A. Cobb; Jennifer M. Kachergus; Owen A. Ross; Christian Wider; Rachel A. Gibson; Faycal Hentati; Matthew J. Farrer


Book ID
116771920
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
335 KB
Volume
477
Category
Article
ISSN
0304-3940

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Glucocerebrosidase Gene L444P mutation i
✍ Qi-Ying Sun; Ji-Feng Guo; Lei Wang; Ren-He Yu; Xing Zuo; Ling-Yan Yao; Qian Pan; 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 457 KB

## Abstract An association between mutations in the __glucocerebrosidase__ (__GBA__) gene and Parkinson's disease (PD) has been reported in several populations. We searched for four common __GBA__ mutations (L444P, F213I, R353W, and N370S) in 402 Chinese PD patients and 413 age‐ and sex‐matched con