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Glial cell line-derived neurotrophic factor protects dopaminergic neurons from 6-hydroxydopamine toxicity in vitro

✍ Scribed by Karla Eggert; Jürgen Schlegel; Wolfgang Oertel; Cornelia Würz; Jürgen-Christian Krieg; Helmut Vedder

Book ID: 117477825
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 391 KB
Volume: 269
Category: Article
ISSN: 0304-3940
DOI: 10.1016/s0304-3940(99)00443-7

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## Abstract The transcription factor Pitx3 is crucial for the development and differentiation of dopamine (DA) neurons. Our previous work has shown the Pitx3 can up‐regulate the expression of brain‐derived neurotrophic factor (BDNF) and glial cell line‐derived neurotrophic factor (GDNF) in neurobla