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Microglia-derived glial cell line-derived neurotrophic factor could protect Sprague–Dawley rat astrocyte from in vitro ischemia-induced damage

✍ Scribed by Gilbert A. Lee; Chi-Hsin Lin; Hang-Hsiang Jiang; Hsin-Ju Chao; Chieh-Liang Wu; Chi-Mei Hsueh

Book ID
116766269
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
109 KB
Volume
356
Category
Article
ISSN
0304-3940

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## Abstract Glial cell line‐derived neurotrophic factor (GDNF) promotes the survival and functions of neurons. It has been shown to be a promising candidate in the treatment of ischemia and other neurodegenerative diseases. We transfected mouse astrocytes in primary cultures with a human GDNF gene