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Glial Cell Line Derived Neurotrophic Factor Prevents High Fat Diet Induced Obesity

✍ Scribed by Simon M. Mwangi; Smitha Marri; Behtash G. Nezami; Ping P. Fu; Javelin C. Cheng; Mala Shanmugam; Shanthi V. Sitaraman; Frank A. Anania; Shanthi Srinivasan

Book ID: 119432025
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 232 KB
Volume: 140
Category: Article
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(11)60177-7

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## Abstract Glial cell line‐derived neurotrophic factor (GDNF) promotes the survival and functions of neurons. It has been shown to be a promising candidate in the treatment of ischemia and other neurodegenerative diseases. We transfected mouse astrocytes in primary cultures with a human GDNF gene