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Glial cell line-derived neurotrophic factor-induced signaling in Schwann cells

✍ Scribed by T. Iwase; C. G. Jung; H. Bae; M. Zhang; B. Soliven


Book ID
111179052
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
485 KB
Volume
94
Category
Article
ISSN
0022-3042

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Glial cell line-derived neurotrophic factor (GDNF) was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is a more potent survival factor for dopaminergic neurons and the noradrenerg