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Gli1 contributes to the invasiveness of pancreatic cancer through matrix metalloproteinase-9 activation

✍ Scribed by Shuntaro Nagai; Masafumi Nakamura; Kosuke Yanai; Junji Wada; Takashi Akiyoshi; Hiroshi Nakashima; Kenoki Ohuchida; Norihiro Sato; Masao Tanaka; Mitsuo Katano


Book ID
108584204
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
467 KB
Volume
99
Category
Article
ISSN
1347-9032

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TGF-β–induced invasiveness of pancreatic
✍ Volker Ellenrieder; Sandra F. Hendler; Claudia Ruhland; Wolfgang Boeck; Guido Ad πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 216 KB

TGF-beta strongly promotes local tumor progression in advanced epithelial tumors, though the underlying mechanisms are poorly understood. In the present study, we demonstrate the potential of TGF-beta to increase the invasiveness of the pancreatic cancer cell lines PANC-1 and IMIM-PC1. TGF-beta-indu