GLC determination of griseofulvin in human plasma
โ Scribed by H. J. Schwarz; B. A. Waldman; V. Madrid
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 292 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0022-3549
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๐ SIMILAR VOLUMES
A GLC method for phenylbutazone at concentrations down to 10 ng/ml in human plasma is described. After addition of an internal standard, phenylbutazone is extracted at pH 5 into benzene. The dry extract is dissolved in benzene, and phenylbutazone is determined by GLC using a 63Ni-electron-capture de
Human plasma was made alkaline and extracted with methylene chloride. To the extract was added the internal standard, cinchonine, followed by evaporation to dryness. The resultant residue was dissolved in a methanolic solution containing trimethylanilinium hydroxide. This solution was assayed by GLC