GLC determination of phenylbutazone in human plasma

✍ Scribed by Antoine Sioufi; Francoise Caudal; Francoise Marfil

• Publisher: John Wiley and Sons
• Year: 1978
• Tongue: English
• Weight: 334 KB
• Volume: 67
• Category: Article
• ISSN: 0022-3549
• DOI: 10.1002/jps.2600670230

✦ Synopsis

A GLC method for phenylbutazone at concentrations down to 10 ng/ml in human plasma is described. After addition of an internal standard, phenylbutazone is extracted at pH 5 into benzene. The dry extract is dissolved in benzene, and phenylbutazone is determined by GLC using a 63Ni-electron-capture detector.