𝔖 Bobbio Scriptorium
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Glass ceramic bone implants. A light microscopic study

✍ Scribed by Greenlee, T. K. ;Beckham, C. A. ;Crebo, A. R. ;Malmorg, J. C.

Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
651 KB
Volume
6
Category
Article
ISSN
0021-9304

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✦ Synopsis

Abstract

Glass ceramic implants containing 45% SiO~2~ with a Ca/P ration of 5 become firmly fixed to bone when placed in a cortical defect of an intact rat femur. The addition of fluoride ions to the implant prevents this fixation. The most significant difference between the two compositions is in their solubilites. The presence of high local concentractions of Ca and PO~4~ ions at the interface of the soluble non‐fluoride containing implant, could account for the deposition of bone at its surface.

It is not felt from these studies, however, that this model will be usable as a mass screening tecunique for evaluating materials variables. It is felt that other less laborous in vitro systems need to be devised.

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