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Germline polymorphisms ofRETandGFRA1genes in patients with medullary thyroid carcinoma

✍ Scribed by N. V. Severskaya; V. A. Saenko; A. A. Ilyin; I. V. Chebotareva; P. O. Rumyantsev; P. A. Isaev; V. S. Medvedev; S. Yamashita


Book ID
110174339
Publisher
SP MAIK Nauka/Interperiodica
Year
2006
Tongue
English
Weight
179 KB
Volume
40
Category
Article
ISSN
0026-8933

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Medullary thyroid carcinoma (MTC) is an uncommon tumour of calcitonin-secreting C-cells of the thyroid gland. This cancer represents an important potential model for the study of mechanisms of human epithelial cell transformation. Although recent studies have identified the gene involved in familial