𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Emergence of medullary thyroid carcinoma in a family with the Cys630Arg RET germline mutation

✍ Scribed by Andreas Machens; Ulrich Schneyer; Hans-Jürgen Holzhausen; Friedhelm Raue; Henning Dralle


Book ID
113919800
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
198 KB
Volume
136
Category
Article
ISSN
0039-6060

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Cys 618 Arg mutation in the RET proto-on
✍ Hava Peretz; Rafael Luboshitsky; Ela Baron; Amnon Biton; Ruth Gershoni; Saly Ush 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 142 KB 👁 2 views

The multiple endocrine neoplasia type 2 (MEN2) syndromes and Hirschsprung's disease (HSCR) are inherited neurocristopathies characterized by medullary thyroid carcinoma (MTC), pheochromocytoma, parathyroid disease, and gastrointestinal neuromatosis. Mutations in the RET proto-oncogene are the underl

Mutation of the RET protooncogene in spo
✍ Charis Eng; Lois M. Mulligan; Darrin P. Smith; Catherine S. Healey; Andrea Frill 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 375 KB

Medullary thyroid carcinoma (MTC) occurs sporadically or as part of the inherited cancer syndrome multiple endocrine neoplasia (MEN) type 2. In MEN 2A, germline missense mutations are found in one of five cysteine codons within exons 10 and I I in the extracellular domain of the RET protooncogene. I