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Germline p53 mutation at codon 133 in a cancer-prone family

✍ Scribed by Y. Saeki; Kazuo Tamura; Yoshihiro Yamamoto; Takuya Hatada; Jun-ichi Furuyama; Joji Utsunomiya


Book ID
105797269
Publisher
Springer
Year
1997
Tongue
English
Weight
272 KB
Volume
75
Category
Article
ISSN
0946-2716

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Mutation at codon 249 of p53 gene in a h
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G-to-T transversion at codon 249 of the p53 gene has been shown to be specifically associated with human hepatocellular carcinomas, particularly that subset associated with exposure to the chemical hepatocarcinogen aflatoxin B,. We surveyed 47 North American adult hepatocellular carcinomas and three