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Genetic counseling and testing for germline p16 mutations in two pancreatic cancer-prone families

✍ Scribed by H.T. Lynch; R.E. Brand; J.F. Lynch; R.M. Fusaro; T.C. Smyrk; M. Goggins; S.E. Kern


Book ID
119756005
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
161 KB
Volume
119
Category
Article
ISSN
0016-5085

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## Abstract Index cases from a clinically relevant cohort of 102 Spanish families with at least 3 cases of breast and/or ovarian cancer (at least 1 case diagnosed before age 50) in the same lineage were screened for germline mutations in the entire coding sequence and intron boundaries of the breas