𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Germline mutations of the RET proto-oncogene in eight Japanese patients with multiple endocrine neoplasia type 2A (MEN2A)

✍ Scribed by Syuya Takiguchi-Shirahama; Kumiko Koyama; Akira Miyauchi; Takanobu Wakasugi; Seiichi Oishi; Hiroshi Takami; Kazumasa Hikiji; Yusuke Nakamura


Publisher
Springer
Year
1995
Tongue
English
Weight
473 KB
Volume
95
Category
Article
ISSN
0340-6717

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Mutations of the RET proto-oncogene in t
✍ Charis Eng; Lois M. Mulligan πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 225 KB πŸ‘ 2 views

## Communicated by Martin Bobrow The RET proto-oncogene codes for a receptor tyrosine kinase thought to play a role in the development of neural crest and its derivatives. Mutations in the RET proto-oncogene have been found in patients with the multiple endocrine neoplasia type 2 syndromes (MEN 2)

Diagnosis of multiple endocrine neoplasi
✍ Marios Kambouris; Charles E. Jackson; Gerald L. Feldman πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 1006 KB

Communicated by B w e A.J. Pondei Multiple endocrine neoplasia type 2 [MEN 21 is an autosomal dominant cancer syndrome with two subtypes, 2A and 2B. MEN 2A and medullary thyroid cancer [MTC] are caused by >25 different point mutations in exons 10, 11, and 13 of the RET proto-oncogene, whereas MEN 2B

Duplication of 9 base pairs in the criti
✍ Dr. Wolfgang HΓΆppner; Henning Dralle; Georg Brabant πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 475 KB

## Communicated b~ R.G.H. Cotton Activating germline mutations in the cysteine-rich domain of the RET proto-oncogene cause endocrine neoplasia type 2A, an autosomal dominant inherited cancer syndrome affecting cells derived from the neural crest, including medullary thyraid carcinoma