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Germline mutation of the PTEN gene in Japanese patients with Cowden disease

โœ Scribed by Hamano, N.; Okada, T.; Suzuki, A.; Takeda, Y.; Mabuchi, H.

Book ID
123494867
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
173 KB
Volume
114
Category
Article
ISSN
0016-5085

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A novel PTEN mutation in a Japanese pati
A novel PTEN mutation in a Japanese patient with Cowden disease
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## Abstract Cowden disease (CD) is an autosomal dominant syndrome characterized by multiple hamartomatous lesions and an increased risk for malignancies. Recent evidence has indicated that the PTEN gene, encoding a protein tyrosine phosphatase, is the CD susceptibility gene. However, another line o