✦ LIBER ✦

Germline Mutations of thePTEN/MMAC1Gene in Japanese Patients with Cowden Disease

✍ Scribed by Kohno, Takashi ;Takahashi, Mina ;Fukutomi, Takashi ;Ushio, Kyosuke ;Yokota, Jun

Book ID: 108581652
Publisher: Wiley (Blackwell Publishing)
Year: 1998
Tongue: English
Weight: 68 KB
Volume: 89
Category: Article
ISSN: 0910-5050
DOI: 10.1111/j.1349-7006.1998.tb03285.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Mutation Analysis of thePTEN/MMAC1Gene i

Mutation Analysis of thePTEN/MMAC1Gene in Japanese Patients with Cowden Disease

✍ Sawada, Takeshi ;Hamano, Naomichi ;Satoh, Hiro ;Okada, Toshihide ;Takeda, Yasuo 📂 Article 📅 2000 🏛 Wiley (Blackwell Publishing) 🌐 English ⚖ 86 KB

Novel germline mutation of thePTENgene i

Novel germline mutation of thePTENgene in a Japanese family with Cowden disease

✍ Naohiko Harada; Takashi Sugimura; Rie Yoshimura; Seiji Motomura; Shuya Shirahama 📂 Article 📅 2003 🏛 Springer Japan 🌐 English ⚖ 291 KB

Two novel mutations ofPTEN gene in Japan

Two novel mutations ofPTEN gene in Japanese patients with Cowden syndrome

✍ Sawada, Takeshi ;Okada, Toshihide ;Miwa, Kazuhiro ;Satoh, Hiro ;Asano, Akimichi 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 90 KB 👁 2 views

Somatic Mutations of thePTEN/MMAC1Gene i

Somatic Mutations of thePTEN/MMAC1Gene in Fifteen Japanese Endometrial Cancers: Evidence for Inactivation of Both Alleles

✍ Kurose, Keisuke ;Bando, Koichi ;Fukino, Koichi ;Sugisaki, Yuichi ;Araki, Tsutomu 📂 Article 📅 1998 🏛 Wiley (Blackwell Publishing) 🌐 English ⚖ 260 KB

A novel PTEN mutation in a Japanese pati

A novel PTEN mutation in a Japanese patient with Cowden disease

✍ Y. Kubo; Y. Urano; Y. Hida; T. Ikeuchi; M. Nomoto; K. Kunitomo; S. Arase 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 446 KB

## Abstract Cowden disease (CD) is an autosomal dominant syndrome characterized by multiple hamartomatous lesions and an increased risk for malignancies. Recent evidence has indicated that the PTEN gene, encoding a protein tyrosine phosphatase, is the CD susceptibility gene. However, another line o

Allelic imbalance, including deletion of

Allelic imbalance, including deletion of PTEN/MMAC1, at the Cowden disease locus on 10q22-23, in hamartomas from patients with cowden syndrome and germline PTEN mutation

✍ Debbie J. Marsh; Patricia L. M. Dahia; Valérie Coulon; Zimu Zheng; Françoise Dor 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 174 KB 👁 3 views

Cowden disease (CD) is a rare, autosomal dominant inherited cancer syndrome characterized by multiple benign and malignant lesions in a wide spectrum of tissues. While individuals with CD have an increased risk of breast and thyroid neoplasms, the primary features of CD are hamartomas. The gene for