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Mutation Analysis of thePTEN/MMAC1Gene in Japanese Patients with Cowden Disease

โœ Scribed by Sawada, Takeshi ;Hamano, Naomichi ;Satoh, Hiro ;Okada, Toshihide ;Takeda, Yasuo ;Mabuchi, Hiroshi


Book ID
108581940
Publisher
Wiley (Blackwell Publishing)
Year
2000
Tongue
English
Weight
86 KB
Volume
91
Category
Article
ISSN
0910-5050

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## Abstract Cowden disease (CD) is an autosomal dominant syndrome characterized by multiple hamartomatous lesions and an increased risk for malignancies. Recent evidence has indicated that the PTEN gene, encoding a protein tyrosine phosphatase, is the CD susceptibility gene. However, another line o