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Germacrane-Type Sesquiterpenes from Curcuma wenyujin

✍ Scribed by Yan Lou; Feng Zhao; Zhaohua Wu; Kai-Feng Peng; Xing-Chuan Wei; Li-Xia Chen; Feng Qiu

Publisher
John Wiley and Sons
Year
2009
Tongue
German
Weight
181 KB
Volume
92
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Two new germacrane‐type sesquiterpene lactones, curdionolides A and B (1 and 2, resp.), and a novel germacrane‐type sesquiterpene lactam, curdionolide C (3), were isolated from Curcuma wenyujin. Y. H. Chen et C. Ling together with five known germacrane‐type sesquiterpenes, 4–8. The structures of the new compounds were elucidated by spectroscopic methods. The inhibitory effects of compounds 1–8 on nitric oxide (NO) production in lipopolysaccharide‐activated macrophages were evaluated.

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