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Four New Sesquiterpenes from Curcuma wenyujin and Their Inhibitory Effects on Nitric-Oxide Production

✍ Scribed by Yan Lou; Feng Zhao; Hao He; Kai-Feng Peng; Li-Xia Chen; Feng Qiu

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
228 KB
Volume
7
Category
Article
ISSN
1612-1872

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✦ Synopsis

Abstract

Four new sesquiterpenes including the novel sesquiterpene lactone (6__R__)‐dehydroxysipanolinolide (1), two new eudesmane‐type sesquiterpenes, curcolide (2) and curcodione (3), and a new xanthane‐type sesquiterpene, curcumadionol (4), were isolated from Curcuma wenyujin Y. H. Chen et C. Ling, together with five known ones, 5–9. The structures of the new compounds were elucidated by spectroscopic methods. The inhibitory effects of compounds 1–9 on nitric‐oxide production in lipopolysaccaride‐activated macrophages were evaluated.

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Four New Cryptoporic Acid Derivatives from the Fruiting Bodies of Cryptoporus sinensis, and Their Inhibitory Effects on Nitric Oxide Production
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## Abstract Four new drimane‐type sesquiterpenoid ethers of isocitric acid, named cryptoporic acids J–M, were isolated from the fruiting bodies of __Cryptoporus sinensis__, together with six known cryptoporic acids. Their structures were elucidated on the basis of extensive spectroscopic analyses.