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Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A

✍ Scribed by Mulligan, Lois M.; Kwok, John B. J.; Healey, Catherine S.; Elsdon, Mark J.; Eng, Charis; Gardner, Emily; Love, Donald R.; Mole, Sara E.; Moore, Julie K.; Papi, Laura; Ponder, Margaret A.; Telenius, Hakan; Tunnacliffe, Alan; Ponder, Bruce A. J.

Book ID: 120643700
Publisher: Nature Publishing Group
Year: 1993
Tongue: English
Weight: 371 KB
Volume: 363
Category: Article
ISSN: 0028-0836
DOI: 10.1038/363458a0

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## Communicated by Martin Bobrow The RET proto-oncogene codes for a receptor tyrosine kinase thought to play a role in the development of neural crest and its derivatives. Mutations in the RET proto-oncogene have been found in patients with the multiple endocrine neoplasia type 2 syndromes (MEN 2)