## Abstract The recent completion of the first rough draft of the human genome has provided fundamental information regarding our genetic makeβup; however, the postβgenome era will certainly require a host of new technologies to address complex biological questions. In particular, a rapid and accur
Genotyping of Simple and Compound Short Tandem Repeat Loci Using Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
β Scribed by Null, Allison P.; Hannis, James C.; Muddiman, David C.
- Book ID
- 125900105
- Publisher
- American Chemical Society
- Year
- 2001
- Tongue
- English
- Weight
- 122 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0003-2700
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Electrospray ionization coupled with Fourier transform ion cyclotron resonance (FTICR) m a s spectrometry has been used to provide infonntion about complete combinatorial libraries of small peptides containing l@-104 components. The fidelity of attempted synthesis steps can be ascertained rapidly, a
A model experiment for the 'on-line' screening of substrate libraries by enzymes using combinatorial libraries in combination with electrospray ionization-Fourier transform ion cyclotron resonance (ESI-FTICR) mass spectrometry has been performed. The reaction between the electrophilic substrate 1-ch