## Abstract Multiple myeloma (MM) is a malignant plasma cell disorder characterized by complex karyotypes and chromosome 1 instability at the cytogenetic level. Chromosome 1 instability generally involves partial duplications, whole‐arm translocations, or jumping translocations of 1q, identified by
Genomic instability within the short arm of chromosome 1 in colorectal cancer
✍ Scribed by Elisa Hess; Lena Brückner; Manfred Schwab; Larissa Savelyeva
- Book ID
- 113513909
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 36 KB
- Volume
- 203
- Category
- Article
- ISSN
- 0165-4608
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A paracentric inversion of the short arm of chromosome 1 (inv(1)(p22p36)) is reported in a deeply mentally retarded 19-year-old girl and in her normal father.
The zygosity of 19 colorectal carcinomas (either near-diploid or polyploid) from patients known to be heterozygous for RFLPs located on chromosome 18 or on the short arm of chromosome 17 has been examined. In most cases, at least one allele was significantly under-represented. The reason for the abs
Cytogenetic analyses of human colon cancer cells have revealed non-random deletions in chromosome arm 8p, among other chromosomal changes. By using 8p-specific DNA probes we could identify allelic loss in 87% of colon cancer cell lines. Corresponding analyses in direct preparations of colon tumor ti