Genomic instability and colorectal cancer
β Scribed by William M. Grady
- Book ID
- 107535612
- Publisher
- Current Science Inc.
- Year
- 2006
- Tongue
- English
- Weight
- 104 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1556-3790
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Genomic instability plays a major role in cancer by facilitating tumor progression and tumor heterogeneity. Inter-simple sequence repeat (inter-SSR) PCR has been developed to provide a rapid and reproducible technique for quantitation of the major type of genomic instability observed in sporadic tum
Microsatellite instability in a subset of colorectal cancers from North America, Europe and Japan has been reported. We examined 88 colorectal cancers from Turkish patients. Five different microsatellite loci (I mono-and 4 dinucleotide repeat regions) were tested. Eight tumors displayed replication