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Genistein arrests hepatoma cells at G2/M phase: involvement of ATM activation and upregulation of p21waf1/cip1 and Wee1

✍ Scribed by Kee-Lung Chang; Mei-Lang Kung; Nan-Haw Chow; Shu-Jem Su


Book ID
113486990
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
583 KB
Volume
67
Category
Article
ISSN
0006-2952

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Genistein inhibits proliferation similar
✍ Zhi-Ming Shao; Mary L. Alpaugh; Joseph A. Fontana; Sanford H. Barsky πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 222 KB

Genistein has been proposed to be responsible for lowering the rate of breast cancer in Asian women but the mechanism for this chemopreventive effect in vivo is unknown. In this study, we present in vitro evidence that genistein inhibits cell proliferation similarly in ER-positive and ER-negative hu