Genetics of congenital nemaline myopathy
โ Scribed by Dr. Kiyotaro Kondo; Tatsuhiko Yuasa
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 732 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0148-639X
No coin nor oath required. For personal study only.
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Skeletal muscle obtained from 2 patients with congenital nernaline rnyopathy (CNM) and from a healthy control was analyzed by 1-and 2dimensional gel electrophoresis. In total extracts, an increase of aactinin by a factor of 2:3 was found for CNM muscle as compared with the control. One-and two-dimen
A 59-year-old man with severe neck extensor weakness had findings diagnostic of nemaline myopathy on muscle biopsy. Review of the literature shows that dropped head occurs in nearly half of the patients with adult-onset nemaline myopathy. Other leading causes of dropped head syndrome are amyotrophic