Congenital nemaline myopathy. I. Defective organization of α-actinin is restricted to muscle

Congenital nemaline myopathy. II. Quanti

Congenital nemaline myopathy. II. Quantitative changes in α-actinin and myosin in skeletal muscle

✍ Dr. Ingo Stuhlfauth; Dr. Frans G. I. Jennekens; Dr. Jacobus Willemse; Dr. Brigit 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 647 KB

Skeletal muscle obtained from 2 patients with congenital nernaline rnyopathy (CNM) and from a healthy control was analyzed by 1-and 2dimensional gel electrophoresis. In total extracts, an increase of aactinin by a factor of 2:3 was found for CNM muscle as compared with the control. One-and two-dimen