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Genetic Variations in the Hypoxia-Inducible Factor-1 Gene and Lung Cancer

✍ Scribed by Konac, E.; Dogan, I.; Onen, H. I.; Yurdakul, A. S.; Ozturk, C.; Varol, A.; Ekmecki, A.


Book ID
121353142
Publisher
Royal Society of Medicine Press
Year
2009
Tongue
English
Weight
191 KB
Volume
234
Category
Article
ISSN
1535-3702

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## Abstract With an incidence of about 300 000 new cases colorectal cancer (CRC) is the second leading cause of cancer‐related death in Europe and the United States. Environmental and genetic factors influence CRC risk. Hypoxia‐inducible factor‐1 (HIF‐1), a heterodimeric protein composed of two sub