Carolina) discussed the relationship of oncogenes and breast cancer. Specifically, he described much of the recent work with HER-2/neu, PRADI, and p53. Some of these genetic lesions appear early in the breast cancer process and are stable as the tumors become invasive and metastasize. Dr. Liu also p
Genetic surrogate endpoint biomarkers in early breast neoplasia
โ Scribed by D. Craig Allred
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 105 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0730-2312
No coin nor oath required. For personal study only.
โฆ Synopsis
Genetic Surrogate Endpoint Biomarkers in Early Breast Neoplasia
"Biomarkers in Early Breast Neoplasia," presented by D. Craig Allred. The biological mechanisms of breast cancer evolution are poorly understood. Furthermore, this problem has been difficult to study because potential precursor lesions of fully developed invasive breast cancer have not been unequivocally identified, and candidate precursors have been difficult to evaluate due to their microscopic dimensions. The involvement of known cancer-associated genes in these lesions can still be comprehensively studied by established methods, such as immunohistochemistry
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