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Genetic regulation of endothelin-1 in vascular endothelial cells

โœ Scribed by Robert J. Hilkert; Mu-En Lee; Thomas Quertermous


Book ID
113409380
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
827 KB
Volume
2
Category
Article
ISSN
1050-1738

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Endothelin-1 (ET-1) is a potent vasoconstrictor peptide synthesized and secreted by vascular endothelial cells. Regulation of ET-1 production occurs at the level of gene transcription. We previously demonstrated a role for arachidonic acid as an intracellular mediator in the regulation of gene expre