Genetic polymorphism of hOGG1 and risk of pterygium in Chinese
β Scribed by Kau, H-C; Tsai, C-C; Hsu, W-M; Liu, J-H; Wei, Y-H
- Book ID
- 110035377
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 87 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0950-222X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Ser326Cys polymorphism in the hOGG1 gene, which is involved in the repair of 8-hydroxyguanine in oxidatively damaged DNA, has been identified and the variant genotype appears to be related to susceptibility to certain cancers. We investigated the association between Ser326Cys polymorphism and squamo
## Abstract Oxidative stress is involved in many types of DNA damage, __e.g.,__ resulting in 8βhydroxyguanine adducts. Since a human counterpart exists for the yeast gene __OGG1__ (__hOGG1__) encoding an enzyme that repairs 8βhydroxyguanine, its polymorphism, Ser^326^Cys, might have potential as a