Genetic polymorphism of desialyzed alpha2 HS-glycoprotein by ultrathin isoelectric focusing
โ Scribed by Sebetan, I.M. ;Heshmat, M.M.
- Publisher
- Springer-Verlag
- Year
- 1988
- Tongue
- English
- Weight
- 201 KB
- Volume
- 101
- Category
- Article
- ISSN
- 1437-1596
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โฆ Synopsis
The genetically determined polymorphism of alpha 2 HS-glycoprotein was analyzed by immunoblotting ultrathin-layer polyacrylamide gel isoelectric focusing in the pH range 4-6.5 and neuraminidase pretreated sera. In a Libyan population sample from Tripoli (n = 110) three common phenotypes, alpha 2 HSG 1-1, 2-1, and 2-2, were observed. The allele frequencies were alpha 2 HSG1 = 0.8364 and alpha 2 HSG2 = 0.1636. The theoretical exclusion rate in cases of disputed paternity is 11.8%.
๐ SIMILAR VOLUMES
Desialyzed plasma specimens were phenotyped for alpha 2HS-glycoprotein (AHS) using polyacrylamide isoelectric focusing (IEF) in the range pH 5-6 in 2.5 M urea, followed by immunoblotting. The technique used in this study is easy to perform and can differentiate the gene products of all the currently
The distribution of plasminogen phenotypes in the population of Veneto was investigated by ultrathin-layer isoelectric focusing. In our sample (n = 1325), the three common phenotypes PLG1, PLG2, PLG2-1 and two further phenotypes PLG1-V and PLG2-V were, observed and the following frequencies calculat