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Genetic polymorphism of CYP2D6: a critical factor for early metastatic relapse in patients treated with adjuvant tamoxifen

✍ Scribed by M. Debled; V. Le Morvan; A. Laurand; G. MacGrogan; V. Brouste; J. Robert; L. Mauriac


Book ID
119597831
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
55 KB
Volume
6
Category
Article
ISSN
1359-6349

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Genetic polymorphisms of CYP2D6*10 and C
✍ Matthew Goetz; Vera Suman πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 56 KB πŸ‘ 1 views

The study by Okishiro et al 1 concludes that the cytochrome P450 (CYP) genotype CYP2D6\*10/\*10 is unlikely to have a clinically significant impact on prognosis in women with breast cancer who receive adjuvant tamoxifen. However, several aspects of the study by Okishiro et al call their conclusions