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CYP2D6 gene variants: association with breast cancer specific survival in a cohort of breast cancer patients from the United Kingdom treated with adjuvant tamoxifen

✍ Scribed by Jean E Abraham, Mel J Maranian, Kristy E Driver, Radka Platte…


Book ID
120699034
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
505 KB
Volume
12
Category
Article
ISSN
1465-5411

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Genetic polymorphisms of CYP2D6*10 and C
✍ Matthew Goetz; Vera Suman 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 56 KB 👁 1 views

The study by Okishiro et al 1 concludes that the cytochrome P450 (CYP) genotype CYP2D6\*10/\*10 is unlikely to have a clinically significant impact on prognosis in women with breast cancer who receive adjuvant tamoxifen. However, several aspects of the study by Okishiro et al call their conclusions