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105 Association of the germline MDM2 SNP309 and TP53 R72P variants with breast cancer survival in specific tumour subgroups

✍ Scribed by A.J. van den Broek; A. Broeks; H. Horlings; L.M. Braaf; L.J. Van't Veer; M.K. Schmidt

Book ID: 119601122
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 46 KB
Volume: 8
Category: Article
ISSN: 1359-6349
DOI: 10.1016/s1359-6349(10)70136-1

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## Abstract Disease expression in hereditary nonpolyposis colorectal cancer (HNPCC) cannot be readily explained by mutation site in the respective DNA mismatch repair genes associated with this disorder. One explanation is the role of modifying genes that can either promote or prevent disease devel